Liposomal Technology - Things to Know

Liposomal Technology - Things to Know

Liposomes are delivery vehicles that are specialized to serve multiple roles in enhancing the capabilities of APIs or Active Pharmaceutical Ingredients. Liposomal technology works by being lipid bilayers that are built-in hollow spherical shapes, which encapsulate the supplement inside a lipid bilayer or aqueous interior.

Used for better delivery, liposomes are known for their ability to make supplements act more effectively. They help in the protection of the molecules from getting externally degraded.

Liposomal Technology Causes Easier Oral Administration

As medical science advances, pharmaceutical companies look for better ways to administer supplements. Liposomal supplements make it easier to do so. Here’s how oral supplement administration is easier with this technology:

Oral administration of supplements is the first thing a patient has to comply with. This delivery system makes it easy to do so.

Liposomal technology increases the bioavailability of the therapeutic agents. This greatly improves the efficacy of the said supplement and reduces side effects.

The technology also works at increasing oral absorption. This happens because it is protected inside the GI tract. This increases the cellular contact and residence time it spends. Because of this, the absorption is higher.

Liposomal technology increases the solubility of supplements that have poor solubility. This makes the them suitable for intake.

Liposomal technology provides pharmaceutical companies unique opportunities to deliver directly into cells or the cellular membrane. It is a wonderful delivery system and is being consistently used by clinics.  

Liposomes were invented as a means to deal with the low bioavailability and limited solubility of supplements. Both these issues were common and pharmaceutical companies worked hard to come up with a technology that increased the efficacy of active ingredients.

Also, liposomes are a delivery system and that helps in increasing gastrointestinal permeability.

Types Of Delivery Systems with Liposomal Technology

Liposomal supplements are one of the most well-researched delivery systems at the moment and they serve a variety of purposes for pharmaceutical companies and clinics. There are four types of active ingredients delivery systems:

  1. Sterically Stabilized Liposomes: These are known for their stability and to cause enhancement of the circulation of the active ingredients in blood.
  2. Conventional Liposomes: These were the first type of liposomal to be invented. They are made from a lipid bilayer that may be composed of cholesterol, neutral lipid, anionic or catatonic lipid. This type improves the therapeutic index of supplements.
  3. Ligand Targeted Liposomes: They are known for site-specific delivery and are a boon to the medical industry.

Noteworthy Benefits of Liposomal Technology

Liposomal supplements offer complete protection to active ingredients like vitamins, bile salts, digestive enzymes, etc against degradation that can happen in the gastrointestinal tract. 

Furthermore, these supplements offer better results as compared to other dietary supplements because of the enhanced rate of absorption. The best part is that liposomal technology assists ingestion or packing without the use of additives like sugars, gelatins, flavors, binders, etc. Thus, it is considered as a wonderful way of improving overall health by enhanced absorption and bioavailability.  

Increase In Bioavailability

The most important reason why liposomal technology has been researched for over 50 years is that they increase bioavailability. It is a subcategory of absorption, and it is defined as the percentage of the administered active ingredients that are able to reach the systemic circulation.

When such a supplement is administered to a patient intravenously, the bioavailability is 100%. But when it is given orally, it can drop by a big percentage. Liposomal technology works at increasing the bioavailability.

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